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⚠️ Not investment advice. Past performance does not guarantee future results.
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Exelixis EXEL

United States Healthcare
7.4/10
AI Analyst score
58.16 USD
Last price at analysis date · analyst target 53.69 (-7.7%)
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🟡 HOLD — Hold, with attention to the regulatory evolution of zanzalintinib and the company's ability to diversify beyond cabozantinib.

Exelixis is a US biopharmaceutical company focused on developing and commercializing oncology therapies, whose main product is cabozantinib, a kinase inhibitor approved for several types of cancer. Exelixis shows solid financial health (net cash, DN/EBITDA -0.66) and exceptional quality (ROE 44.39%, gross margin 96.48%), with revenue growth of 10.6% and earnings growth of 26.2%. However, the FDA delay for zanzalintinib introduces uncertainty about the timeline of a key product, moderating short-term growth expectations.

Financial health
9.0
Quality / Moat
9.4
Valuation
5.9
Growth
7.2
Dividend
1.5
Momentum
7.3
Risk & Context
8.2

Detailed metrics

Market and fundamental data as of the analysis date.

💵 Valuation
P/E18.29
Fwd P/E13.65
EV/EBITDA13.46
P/B7.85
P/S5.92
PEG2.56
Market cap14.41 B USD
Enterprise value13.74 B USD
🏰 Quality and moat
ROIC (approx.)48.1%
Gross margin96.48%
FCF conversion72%
Operating margin39.51%
📈 Profitability and margins
ROE44.39%
ROA23.97%
Net margin35.33%
FCF739.7 M USD
FCF yield5.13%
🏦 Solvency and liquidity
Total debt165.9 M USD
Net debt-673.5 M USD
Cash839.4 M USD
EBITDA1.02 B USD
Net debt / EBITDA-0.66
D/E9.00
Current ratio3.46
Quick ratio3.24
🚀 Growth
Revenue growth10.60%
Earnings growth26.20%
EPS (TTM)3.18 USD
EPS (Fwd)4.26 USD
💰 Dividend and risk
Dividend yield0.00%
Payout0.0%
Beta0.42
Analyst consensusBuy (16)
Target price53.69 USD
52-week range33.76 USD – 59.72 USD
⚠️ Main risk: Dependence on cabozantinib as the main revenue source and the delay in zanzalintinib's approval, which concentrate risk on the success of the pipeline.
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Full AI report

Generated automatically from the metrics, the macro context and the company's news.

Exelixis is a US biopharmaceutical company focused on developing and commercializing oncology therapies, whose main product is cabozantinib, a kinase inhibitor approved for several types of cancer. Exelixis shows solid financial health (net cash, DN/EBITDA -0.66) and exceptional quality (ROE 44.39%, gross margin 96.48%), with revenue growth of 10.6% and earnings growth of 26.2%. However, the FDA delay for zanzalintinib introduces uncertainty about the timeline of a key product, moderating short-term growth expectations.

Score by category

CategoryScore
Financial health9.0
Quality / Moat9.4
Valuation5.9
Growth7.2
Dividend1.5
Momentum7.3
Risk & Context8.2

OVERALL SCORE: 7.4/10

Context and risks

Specific regulatory risk: the FDA review extension for zanzalintinib introduces uncertainty about the launch timeline of a key product. Additionally, dependence on cabozantinib as the main revenue source concentrates risk on the approval of new drugs.

News considered in the analysis

  • Exelixis (EXEL) Gets FDA Review Extension For Zanzalintinib to metastatic Colorectal Cancer — La extensión de la revisión de la FDA retrasa el lanzamiento de un activo clave, pero la aprobación sigue siendo probable.
  • Exelixis Eyes Oncology Deals, Readies Zanzalintinib Launch as Cabozantinib Tops $3B — El crecimiento de cabozantinib y la preparación para el lanzamiento de zanzalintinib son positivos, aunque la actividad de acuerdos es incierta.
  • Exelixis (EXEL) Faces a Three-Month Zanzalintinib Review Extension. Can the Data Support Approval? — La extensión de tres meses genera incertidumbre sobre el calendario, pero no sobre la eficacia del fármaco.
  • Could Zanzalintinib's FDA Delay Affect Exelixis' Growth Plans? — El retraso regulatorio podría afectar las proyecciones de crecimiento a corto plazo, pero el impacto es moderado.
  • Alpha Teknova (TKNO) Moves 7.1% Higher: Will This Strength Last? — Noticia sobre otra empresa sin relevancia para Exelixis.

Verdict: Hold, with attention to the regulatory evolution of zanzalintinib and the company's ability to diversify beyond cabozantinib.

Main risk: Dependence on cabozantinib as the main revenue source and the delay in zanzalintinib's approval, which concentrate risk on the success of the pipeline.

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Automatically generated analysis from fundamental, market and news data. Not personalised financial advice — a research tool, not an individual recommendation. Past performance does not guarantee future results. Last update of this analysis: 2026-09-28. Legal notice, privacy & cookies.