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⚠️ Not investment advice. Past performance does not guarantee future results.
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Ascendis Pharma ASND

DenmarkHealthcare · BiotechnologyUSD
6.1AI score
Rank 870 of 2,130
better than 55% of companies
228.41USD
▲ 9.0% in one year
ASND MSCI World +22.1%
Average analyst target
305.91 USD (+33.9%)
20 analysts
52-wk low 186.05High 282.15
📈 Chart on TradingView ↗(affiliate link)Analysis of 08/10/2026

What does it do?

Ascendis Pharma is a Danish biopharmaceutical company that develops innovative precision therapies for endocrine and rare diseases, using its prolonged-release technology platform (TransCon) to improve the efficacy and convenience of treatments.

Key points

from its scores
  • ✓Strong growth10.0
  • ✓Very solid balance sheet9.4
  • ✕Little or no dividend1.5
  • ✕Demanding valuation3.4
  • ✕Unfavourable risk and backdrop4.7

AI analysis

bottom line, main risk, context and news
Bottom line

Hold, given the strong growth and solid financial health, but with caution due to the demanding valuation and dependence on regulatory approvals.

Ascendis Pharma shows a solid financial profile with net cash (ND/EBITDA -1.37), gross margins of 91.3%, and revenue growth of 114.7%, although its valuation is demanding (EV/EBITDA 49.55) and free cash flow conversion is weak (4.85). The main risk is regulatory, inherent to its sector.

⚠ Main risk

Regulatory risk: dependence on FDA and EMA approvals for its therapies, along with the possibility of clinical trial setbacks or reimbursement decisions, could significantly impact future revenues.

Context and risks

Ascendis Pharma is a Danish biopharmaceutical company with a global business model and no material exposure to interest rates, commodities, or shipping routes. Its main contextual risk is regulatory, inherent to the biotech sector: the approval and commercialization of its therapies depend on drug agencies (FDA, EMA), and any setback in clinical trials or reimbursement decisions could affect future revenues.

Is Ascendis Pharma stock cheap or expensive?

at the analysis date
Pricier than its sector

On P/E and EV / EBITDA, it trades 104% above the Healthcare median on average.

MultipleCompanySectorDifference
P/E17.526.7−35%
EV / EBITDA49.614.5+242%
Price / sales12.83.4+275%

Sector: median of the 217 Healthcare companies analysed. In bold, the multiples used for the comparison.

Valuation score: 3.4 out of 10 (median for Healthcare: 4.7).

Average analyst target: 305.91 USD, +33.9% versus the price.

A premium can be justified if the company is of higher quality or grows faster than its sector: Quality / Moat 6.6 (sector 5.5), Growth 10.0 (sector 6.6).

Indicative fair value · USD
Graham110.93▼ −51% vs price
Price228.41at the analysis date

Classic formulas with standard assumptions (0.0% growth, 8-9% discount rate). Indicative only: they change a lot with the assumptions and are not a recommendation.

Work out its fair value yourself →How much would you have made investing every month? →

Comparing it with its sector does not say whether it is a good buy: this is not investment advice.

🛒 Where to buy ASNDCheapest · US (NYSE/Nasdaq) · sample 200.00 € orderCheapest · US (NYSE/Nasdaq) · sample 200.00 € orderAvailable in your country · US (NYSE/Nasdaq) · sample 200.00 € order
By the cost of that order: commission and FX, taxes excluded (public fee schedules). Brokers marked «affiliate» may pay Meridian a commission at no cost to you. This is not investment advice. · Compare all 22 brokers by real cost →

Score by category

0 to 10 · hover overtap each one to see what it measures
Financial healthiExcellent9.4Healthcare median: 6.5
Quality / MoatiFair6.6Healthcare median: 5.5
ValuationiPoor3.4Healthcare median: 4.7
GrowthiExcellent10.0Healthcare median: 6.6
DividendiPoor1.5Healthcare median: 1.5
MomentumiFair6.2Healthcare median: 6.2
Risk & ContextiWeak4.7Healthcare median: 7.1
Healthcare median7 or more 5 to 7 under 5

Key metrics

at the analysis date · compared with the Healthcare median
P/Ei
17.5
Healthcare: 26.7below
EV / EBITDAi
49.6
Healthcare: 14.5above
ROEi
118.8%
Healthcare: 10.8%above
Operating margini
65.0%
Healthcare: 15.2%above
Net debt / EBITDAi
−1.37
Healthcare: 1.53net cash
Revenue growthi
+114.7%
Healthcare: +8.8%above

Valuation

P/E
17.5
Forward P/E
21.1
EV / EBITDA
49.6
Price / sales
12.8
Market cap
15.0B USD
Enterprise value
13.1B EUR

Profitability

ROE
118.8%
ROA
9.6%
Gross margin
91.3%
Operating margin
65.0%
Net margin
70.8%
Free cash flow
12.8M EUR
FCF yield
0.1%
Cash conversion
5%

Solvency

Total debt
450.1M EUR
Net debt
−362.2M EUR
Cash
812.3M EUR
EBITDA
263.5M EUR
Net debt / EBITDA
−1.37
Debt / equity
31.33
Current ratio
2.99
Quick ratio
2.23

Growth

Revenue growth
+114.7%
EPS (TTM)
13.05 USD
EPS (forward)
10.82 USD

Dividend

Dividend yield
0.0%
Payout
0.0%

Risk and market

Analyst consensus
Strong buy (20)
Target price
305.91 USD
52-week range
186.05 – 282.15

Compare it with its sector

All 217 in Healthcare →
See the full ranking with filters →

Keep browsing the ranking

sorted by score, highest first

Frequently asked questions about Ascendis Pharma

Is Ascendis Pharma stock cheap or expensive?

On P/E and EV / EBITDA, it trades 104% above the Healthcare median on average. Valuation score: 3.4 out of 10 (median for Healthcare: 4.7). Average analyst target: 305.91 USD, +33.9% versus the price. This is not investment advice.

What score does Ascendis Pharma get on MeridIAn Screener?

It scores 6.1 out of 10, rank 870 of 2,130 (better than 55% of the companies analysed). Its strongest category is Growth (10.0) and its weakest, Dividend (1.5). Analysis of 08/10/2026.

What is Ascendis Pharma's P/E ratio?

Its P/E is 17.5: the share price equals 17.5 times earnings per share over the last 12 months. The Healthcare median is 26.7. Based on the earnings analysts expect, the forward P/E is 21.1.

How much is Ascendis Pharma worth on the stock market?

Its market capitalisation is 15.0B USD and its enterprise value, debt included, is 13.1B USD.

How much debt does Ascendis Pharma have?

It has more cash than debt: net cash of 362.2M EUR.

Does Ascendis Pharma pay a dividend?

It pays no dividend, or almost none.

How has Ascendis Pharma stock performed over the last year?

It has risen 9.0% over the last year, excluding dividends. Over the last 52 weeks it has traded between 186.05 and 282.15 USD. Past performance does not guarantee future results.

What do analysts think of Ascendis Pharma?

20 analysts cover it; their average recommendation is “Strong buy” and their average target is 305.91 USD (+33.9% versus the price). It is an estimate, not market data.