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Insmed INSM

United States Healthcare
4.5/10
AI Analyst score
117.83 USD
Last price at analysis date · analyst target 199.04 (+68.9%)
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🟡 HOLD — Hold; the label expansion for Arikayce is a clear catalyst, but the valuation already prices in a lot of optimism.

Insmed is a biopharmaceutical company focused on developing and commercializing therapies for rare and serious diseases, with Arikayce as its main product for non-tuberculous mycobacterial lung infections. Insmed shows explosive revenue growth (296%) driven by Arikayce, but its profitability is deeply negative (operating margin -23.81%) and its valuation is demanding (forward P/E 153.71), reflecting a high-risk, high-reward profile.

Financial health
5.9
Quality / Moat
3.3
Valuation
2.0
Growth
10.0
Dividend
1.5
Momentum
1.0
Risk & Context
6.8

Detailed metrics

Market and fundamental data as of the analysis date.

💵 Valuation
P/EN/D
Fwd P/E153.71
EV/EBITDA-31.84
P/B33.96
P/S22.62
PEG1.09
Market cap25.73 B USD
Enterprise value25.31 B USD
🏰 Quality and moat
ROIC (approx.)-18.1%
Gross margin83.45%
FCF conversionN/D
Operating margin-23.81%
📈 Profitability and margins
ROE-87.22%
ROA-22.17%
Net margin-76.94%
FCF-571.8 M USD
FCF yield-2.22%
🏦 Solvency and liquidity
Total debt739.7 M USD
Net debt-420.6 M USD
Cash1.16 B USD
EBITDA-795.0 M USD
Net debt / EBITDA0.53
D/E97.65
Current ratio3.72
Quick ratio3.13
🚀 Growth
Revenue growth296.10%
Earnings growthN/D
EPS (TTM)-4.12 USD
EPS (Fwd)0.77 USD
💰 Dividend and risk
Dividend yield0.00%
Payout0.0%
Beta0.82
Analyst consensusStrong buy (23)
Target price199.04 USD
52-week range90.39 USD – 212.75 USD
⚠️ Main risk: The main risk is the dependence on a single drug (Arikayce) and increasing competition in the rare lung disease market, which could limit future growth potential.
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Full AI report

Generated automatically from the metrics, the macro context and the company's news.

Insmed is a biopharmaceutical company focused on developing and commercializing therapies for rare and serious diseases, with Arikayce as its main product for non-tuberculous mycobacterial lung infections. Insmed shows explosive revenue growth (296%) driven by Arikayce, but its profitability is deeply negative (operating margin -23.81%) and its valuation is demanding (forward P/E 153.71), reflecting a high-risk, high-reward profile.

Score by category

CategoryScore
Financial health5.9
Quality / Moat3.3
Valuation2.0
Growth10.0
Dividend1.5
Momentum1.0
Risk & Context6.8

OVERALL SCORE: 4.5/10

Context and risks

The biotech sector is under pressure from renewed concerns about AI safety, which is affecting technology and high-growth stocks. However, Insmed's primary risk is regulatory and competitive, not geopolitical.

News considered in the analysis

  • Insmed (INSM) Gets Faster FDA Review. Can Its Lung Drug Reach More Patients? — La revisión prioritaria de la FDA para la expansión de la etiqueta de Arikayce es un evento regulatorio material que amplía el mercado direccionable del fármaco principal.
  • FDA Accepts Insmed's Filing Seeking Label Expansion for Arikayce — La aceptación de la solicitud por parte de la FDA es un hito regulatorio concreto que respalda el crecimiento futuro de los ingresos de Arikayce.
  • Did FDA Priority Review of ARIKAYCE ENCORE Data Just Shift Insmed's (INSM) Investment Narrative? — El análisis de la narrativa de inversión refleja el impacto potencial de los datos de ENCORE, pero es una evaluación especulativa sobre el sentimiento del mercado.
  • Can LQDA's Yutrepia Outpace Intensifying PAH Competition? — La mención de la creciente competencia en la hipertensión arterial pulmonar (HAP) es un riesgo para el segmento, pero no es específico de Insmed y su efecto es incierto.
  • What BioPharma Credit (BPCP) Said on Its H1 Earnings Call — Titular no relacionado con Insmed; se refiere a un vehículo de inversión en regalías farmacéuticas.

Verdict: Hold; the label expansion for Arikayce is a clear catalyst, but the valuation already prices in a lot of optimism.

Main risk: The main risk is the dependence on a single drug (Arikayce) and increasing competition in the rare lung disease market, which could limit future growth potential.

Other Healthcare companies

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Automatically generated analysis from fundamental, market and news data. Not personalised financial advice — a research tool, not an individual recommendation. Past performance does not guarantee future results. Last update of this analysis: 2026-09-28. Legal notice, privacy & cookies.