⚠️ Not investment advice. This is a quantitative research tool; every decision is the user's own responsibility. Past performance does not guarantee future results.⚠️ Not investment advice. Past performance does not guarantee future results.
⚠️ Not investment advice. Past performance does not guarantee future results.
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Rhythm Pharmaceuticals RYTM

United StatesHealthcare · BiotechnologyUSD
3.6AI score
Rank 2,023 of 2,130
better than 5% of companies
88.45USD
▼ 12.3% in one year
RYTM MSCI World +22.1%
Average analyst target
138.59 USD (+56.7%)
17 analysts
52-wk low 74.50High 122.20
📈 Chart on TradingView ↗(affiliate link)Analysis of 08/10/2026

What does it do?

Rhythm Pharmaceuticals is a biotech focused on developing therapies for obesity and rare hyperphagia disorders, with a business model based on R&D and future drug commercialization.

Key points

from its scores
  • ✓Strong growth9.9
  • ✕Little or no dividend0.5
  • ✕Demanding valuation0.8
  • ✕Unfavourable risk and backdrop2.1

AI analysis

bottom line, main risk, context and news
Bottom line

Hold only for investors with high risk tolerance and a long horizon; the thesis depends on drug approval and commercialization, not on current fundamentals.

RYTM shows very strong revenue growth (46.9%) and an 89% gross margin, but remains in development with deeply negative operating margins (-68.14%) and ROIC of -76.97%, explaining its low valuation (0.8) and quality (3.27) scores. The balance sheet is sound (liquidity 3.45, debt/EBITDA 1.11), but profitability is far off.

⚠ Main risk

The main risk is regulatory and clinical execution: the value depends on its pipeline therapies passing trials and gaining approval, with a very negative operating margin that burns cash.

Context and risks

No recent news and no material exposure to current macro factors: biotech does not depend on rates, commodities, or shipping routes.

Is Rhythm Pharmaceuticals stock cheap or expensive?

at the analysis date
Pricier than its sector

On Price / sales, it trades 640% above the Healthcare median.

MultipleCompanySectorDifference
Price / book59.14.1+1,339%
Price / sales25.33.4+640%

Sector: median of the 217 Healthcare companies analysed. In bold, the multiples used for the comparison.

Valuation score: 0.8 out of 10 (median for Healthcare: 4.7).

Average analyst target: 138.59 USD, +56.7% versus the price.

A premium can be justified if the company is of higher quality or grows faster than its sector: Quality / Moat 3.3 (sector 5.5), Growth 9.9 (sector 6.6).

Work out its fair value yourself →How much would you have made investing every month? →

Comparing it with its sector does not say whether it is a good buy: this is not investment advice.

🛒 Where to buy RYTMCheapest · US (NYSE/Nasdaq) · sample 200.00 € orderCheapest · US (NYSE/Nasdaq) · sample 200.00 € orderAvailable in your country · US (NYSE/Nasdaq) · sample 200.00 € order
By the cost of that order: commission and FX, taxes excluded (public fee schedules). Brokers marked «affiliate» may pay Meridian a commission at no cost to you. This is not investment advice. · Compare all 22 brokers by real cost →

Score by category

0 to 10 · hover overtap each one to see what it measures
Financial healthiFair5.7Healthcare median: 6.5
Quality / MoatiPoor3.3Healthcare median: 5.5
ValuationiPoor0.8Healthcare median: 4.7
GrowthiExcellent9.9Healthcare median: 6.6
DividendiPoor0.5Healthcare median: 1.5
MomentumiPoor3.1Healthcare median: 6.2
Risk & ContextiPoor2.1Healthcare median: 7.1
Healthcare median7 or more 5 to 7 under 5

Key metrics

at the analysis date · compared with the Healthcare median
EV / EBITDAi
−30.0
Healthcare: 14.5below
ROEi
−117.0%
Healthcare: 10.8%below
Operating margini
−68.1%
Healthcare: 15.2%below
Net debt / EBITDAi
1.11
Healthcare: 1.53below
Revenue growthi
+46.9%
Healthcare: +8.8%above
Dividend yieldi
0.0%
Healthcare: 0.0%below

Valuation

Forward P/E
−144.4
EV / EBITDA
−30.0
Price / book
59.1
Price / sales
25.3
Market cap
6.1B USD
Enterprise value
6.0B USD

Profitability

ROE
−117.0%
ROA
−31.0%
ROIC (approx.)
−77.0%
Gross margin
89.0%
Operating margin
−68.1%
Net margin
−85.6%
Free cash flow
−130.6M USD
FCF yield
−2.2%

Solvency

Total debt
109.8M USD
Net debt
−221.1M USD
Cash
330.9M USD
EBITDA
−199.6M USD
Net debt / EBITDA
1.11
Debt / equity
50.52
Current ratio
3.45
Quick ratio
3.00

Growth

Revenue growth
+46.9%
EPS (TTM)
−3.12 USD
EPS (forward)
−0.61 USD

Dividend

Dividend yield
0.0%

Risk and market

Beta
2.01
Analyst consensus
none (17)
Target price
138.59 USD
52-week range
74.50 – 122.20

Compare it with its sector

All 217 in Healthcare →
See the full ranking with filters →

Keep browsing the ranking

sorted by score, highest first

Frequently asked questions about Rhythm Pharmaceuticals

Is Rhythm Pharmaceuticals stock cheap or expensive?

On Price / sales, it trades 640% above the Healthcare median. Valuation score: 0.8 out of 10 (median for Healthcare: 4.7). Average analyst target: 138.59 USD, +56.7% versus the price. This is not investment advice.

What score does Rhythm Pharmaceuticals get on MeridIAn Screener?

It scores 3.6 out of 10, rank 2,023 of 2,130 (better than 5% of the companies analysed). Its strongest category is Growth (9.9) and its weakest, Dividend (0.5). Analysis of 08/10/2026.

How much is Rhythm Pharmaceuticals worth on the stock market?

Its market capitalisation is 6.1B USD and its enterprise value, debt included, is 6.0B USD.

How much debt does Rhythm Pharmaceuticals have?

It has more cash than debt: net cash of 221.1M USD.

Does Rhythm Pharmaceuticals pay a dividend?

It pays no dividend, or almost none.

How has Rhythm Pharmaceuticals stock performed over the last year?

It has fallen 12.3% over the last year, excluding dividends. Over the last 52 weeks it has traded between 74.50 and 122.20 USD. Past performance does not guarantee future results.

What do analysts think of Rhythm Pharmaceuticals?

17 analysts cover it; their average recommendation is “none” and their average target is 138.59 USD (+56.7% versus the price). It is an estimate, not market data.