⚠️ Not investment advice. This is a quantitative research tool; every decision is the user's own responsibility. Past performance does not guarantee future results.⚠️ Not investment advice. Past performance does not guarantee future results.
⚠️ Not investment advice. Past performance does not guarantee future results.
🔓 Free accountRanking, alerts and Top 10Sign up with GoogleSign in

PTC Therapeutics PTCT

United StatesHealthcare · BiotechnologyUSD
4.9AI score
Rank 1,760 of 2,130
better than 17% of companies
63.23USD
▼ 4.5% in one year
PTCT MSCI World +22.1%
Average analyst target
101.79 USD (+61.0%)
14 analysts
52-wk low 61.23High 90.87
📈 Chart on TradingView ↗(affiliate link)Analysis of 08/10/2026

What does it do?

PTC Therapeutics is a biopharmaceutical company that develops and commercializes therapies for rare and genetic diseases, with a business model focused on innovation and the commercialization of medicines for unmet medical needs.

Key points

from its scores
  • ✓Strong growth10.0
  • ✓Favourable backdrop7.9
  • ✕Little or no dividend1.5
  • ✕Demanding valuation1.9
  • ✕Poor share-price trend2.6

AI analysis

bottom line, main risk, context and news
Bottom line

Strong growth and operating margin are attractive, but high debt and demanding valuation limit near-term upside potential.

PTC Therapeutics shows exceptional revenue growth (101.5%) and a solid operating margin (41.3%), but its high leverage (net debt/EBITDA of 4.61) and demanding valuation (EV/EBITDA of 35.66) create financial and valuation risks in a rising rate environment.

⚠ Main risk

The main risk is the high financial leverage (net debt/EBITDA of 4.61), which in a rising interest rate environment could pressure cash flow and limit the ability to invest in its drug pipeline.

Context and risks

PTC Therapeutics operates in the U.S. biotechnology sector, where regulatory risk is inherent: FDA drug approvals and drug pricing pressure can materially affect revenues. The company has net debt of 4.61 times its EBITDA, amplifying its vulnerability to a rising interest rate environment, although its liquidity position (3.39 ratio) provides some cushion.

Is PTC Therapeutics stock cheap or expensive?

at the analysis date
Pricier than its sector

On EV / EBITDA, it trades 146% above the Healthcare median.

MultipleCompanySectorDifference
EV / EBITDA35.714.5+146%
Price / sales5.23.4+53%

Sector: median of the 217 Healthcare companies analysed. In bold, the multiples used for the comparison.

Valuation score: 1.9 out of 10 (median for Healthcare: 4.7).

Average analyst target: 101.79 USD, +61.0% versus the price.

A premium can be justified if the company is of higher quality or grows faster than its sector: Quality / Moat 4.2 (sector 5.5), Growth 10.0 (sector 6.6).

Work out its fair value yourself →How much would you have made investing every month? →

Comparing it with its sector does not say whether it is a good buy: this is not investment advice.

🛒 Where to buy PTCTCheapest · US (NYSE/Nasdaq) · sample 200.00 € orderCheapest · US (NYSE/Nasdaq) · sample 200.00 € orderAvailable in your country · US (NYSE/Nasdaq) · sample 200.00 € order
By the cost of that order: commission and FX, taxes excluded (public fee schedules). Brokers marked «affiliate» may pay Meridian a commission at no cost to you. This is not investment advice. · Compare all 22 brokers by real cost →

Score by category

0 to 10 · hover overtap each one to see what it measures
Financial healthiFair5.8Healthcare median: 6.5
Quality / MoatiWeak4.2Healthcare median: 5.5
ValuationiPoor1.9Healthcare median: 4.7
GrowthiExcellent10.0Healthcare median: 6.6
DividendiPoor1.5Healthcare median: 1.5
MomentumiPoor2.6Healthcare median: 6.2
Risk & ContextiGood7.9Healthcare median: 7.1
Healthcare median7 or more 5 to 7 under 5

Key metrics

at the analysis date · compared with the Healthcare median
EV / EBITDAi
35.7
Healthcare: 14.5above
Operating margini
41.3%
Healthcare: 15.2%above
Net debt / EBITDAi
4.61
Healthcare: 1.53above
Revenue growthi
+101.5%
Healthcare: +8.8%above
Dividend yieldi
0.0%
Healthcare: 0.0%below
Forward P/Ei
23.6
Healthcare: 17.5above

Valuation

Forward P/E
23.6
EV / EBITDA
35.7
Price / book
−31.9
Price / sales
5.2
Market cap
5.3B USD
Enterprise value
6.1B USD

Profitability

ROA
2.5%
Gross margin
50.0%
Operating margin
41.3%
Net margin
−3.8%
Free cash flow
−286.8M USD
FCF yield
−5.4%
Cash conversion
−168%

Solvency

Total debt
3.0B USD
Net debt
788.8M USD
Cash
2.2B USD
EBITDA
171.2M USD
Net debt / EBITDA
4.61
Current ratio
3.39
Quick ratio
3.20

Growth

Revenue growth
+101.5%
EPS (TTM)
−0.65 USD
EPS (forward)
2.68 USD

Dividend

Dividend yield
0.0%
Payout
0.0%

Risk and market

Beta
0.49
Analyst consensus
Buy (14)
Target price
101.79 USD
52-week range
61.23 – 90.87

Compare it with its sector

All 217 in Healthcare →
See the full ranking with filters →

Keep browsing the ranking

sorted by score, highest first

Frequently asked questions about PTC Therapeutics

Is PTC Therapeutics stock cheap or expensive?

On EV / EBITDA, it trades 146% above the Healthcare median. Valuation score: 1.9 out of 10 (median for Healthcare: 4.7). Average analyst target: 101.79 USD, +61.0% versus the price. This is not investment advice.

What score does PTC Therapeutics get on MeridIAn Screener?

It scores 4.9 out of 10, rank 1,760 of 2,130 (better than 17% of the companies analysed). Its strongest category is Growth (10.0) and its weakest, Dividend (1.5). Analysis of 08/10/2026.

How much is PTC Therapeutics worth on the stock market?

Its market capitalisation is 5.3B USD and its enterprise value, debt included, is 6.1B USD.

How much debt does PTC Therapeutics have?

Its net debt (debt minus cash) is 788.8M USD. That is 4.61 times its EBITDA; the Healthcare median is 1.53.

Does PTC Therapeutics pay a dividend?

It pays no dividend, or almost none.

How has PTC Therapeutics stock performed over the last year?

It has fallen 4.5% over the last year, excluding dividends. Over the last 52 weeks it has traded between 61.23 and 90.87 USD. Past performance does not guarantee future results.

What do analysts think of PTC Therapeutics?

14 analysts cover it; their average recommendation is “Buy” and their average target is 101.79 USD (+61.0% versus the price). It is an estimate, not market data.